Leading researcher in notch signaling and carcinogenesis. Assistant Professor of Medicine at University of Chicago

EVGENY IZUMCHENKO

Advisor

Evgeny Izumchenko is an Assistant Professor in the Department of Medicine, Section of Hematology/Oncology, at the University of Chicago. He is one of LongeVC's Advisory Board members.

Evgeny has performed thesis work in the laboratory of Dr Erica Golemis, an internationally recognised cancer biologist, and his studies provided some of the earliest insights on the role of NEDD9 in the early stages of cancer development. He completed his first postdoctoral training with Dr Kevin Brown and Dr Stratford May at the University of Florida, with an NIH postdoctoral fellowship supporting his research.

Evgeny joined the lab of Dr David Sidransky at Johns Hopkins University in 2012, where he carried out seminal work in defining the clonal evolution and heterogeneity in several solid tumour types at both the genetic and epigenetic levels. Based on his record of research accomplishments, he was invited to join the Department of Otolaryngology as an Instructor in 2016 and subsequently was promoted to the rank of Assistant Professor in May 2017. Evgeny became a part of the Department of Medicine at the University of Chicago in 2019.

Evgeny's research focuses on understanding the complex interplay between the genetic and epigenetic alterations in carcinogenesis and disease progression and exploiting this understanding to develop novel biomarkers for diagnosis and risk stratification and identify targets for therapeutic intervention. Specifically, he is interested in defining the drivers underlying premalignant progression and early immune evasion. Evgeny has focused his research on cancers of the upper aerodigestive tract, a very challenging area of oncology.

Evgeny partners with researchers and oncologists in academia and the global pharmaceutical industry to advance the discovery of biomarkers for early cancer detection and risk assessment, personalised therapy, and novel anti-cancer interventions.

Evgeny holds a Bachelor's degree in Laboratory Medicine and a Master's degree in Clinical Biochemistry from the Ben-Gurion University of the Negev. He received a Doctor of Philosophy (PhD) in Molecular Biology and Immunology via the BGU /Fox Chase Cancer Center (FCCC) Partnership Graduate Research Program from the Ben-Gurion University of the Negev.

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